Drugs Of Choice For Seizures & Epilepsy

Science Of Medicine
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*Generalized Seizures*

1. *Tonic-Clonic Seizures*: Valproate, Lamotrigine, or Levetiracetam are commonly used.

2. *Absence Seizures*: Ethosuximide, Valproate, or Lamotrigine are preferred.

3. *Myoclonic Seizures*: Valproate is often the first choice, followed by Levetiracetam or Clonazepam.


*Partial Seizures*

1. *Simple Partial Seizures*: Carbamazepine, Phenytoin, or Valproate are commonly used.

2. *Complex Partial Seizures*: Carbamazepine, Phenytoin, or Lamotrigine are preferred.


*Special Syndromes*

1. *Lennox-Gastaut Syndrome*: Valproate, Lamotrigine, or Topiramate are often used.

2. *West Syndrome*: Adrenocorticotropic hormone (ACTH) or Vigabatrin are commonly used.

3. *Dravet Syndrome*: Stiripentol, Valproate, or Topiramate are preferred.


*Status Epilepticus*

1. *First-line treatment*: Lorazepam or Diazepam (benzodiazepines) are commonly used.

2. *Second-line treatment*: Phenytoin, Fosphenytoin, or Levetiracetam are often used.


*Other Considerations*

1. *Pregnancy*: Lamotrigine, Levetiracetam, or Carbamazepine are often preferred due to their relatively safer profiles.

2. *Children*: Valproate, Lamotrigine, or Levetiracetam are commonly used due to their efficacy and tolerability.

3. *Elderly*: Lamotrigine, Levetiracetam, or Gabapentin are often preferred due to their relatively better tolerability.


Please note that this is not an exhaustive list, and the choice of medication may vary depending on individual patient factors, such as medical history, comorbidities, and potential drug interactions. It's essential to consult a healthcare professional for personalized treatment.


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