Analgesics and Sedatives
1. _Morphine_
- Dose: 0.05-0.2 mg/kg IV bolus, followed by 0.01-0.05 mg/kg/h IV infusion
- Administration: IV injection or infusion
- Use: Pain management, sedation
- Indication: Acute pain, agitation
- Side effects: Respiratory depression, hypotension, constipation
- Antidote: Naloxone (0.4-2 mg IV)
2. _Fentanyl_
- Dose: 0.5-2 mcg/kg IV bolus, followed by 0.5-2 mcg/kg/h IV infusion
- Administration: IV injection or infusion
- Use: Pain management, sedation
- Indication: Acute pain, agitation
- Side effects: Respiratory depression, hypotension, bradycardia
- Antidote: Naloxone (0.4-2 mg IV)
3. _Midazolam_
- Dose: 0.05-0.2 mg/kg IV bolus, followed by 0.01-0.05 mg/kg/h IV infusion
- Administration: IV injection or infusion
- Use: Sedation, anxiolysis
- Indication: Agitation, anxiety
- Side effects: Respiratory depression, hypotension, amnesia
- Antidote: Flumazenil (0.2-1 mg IV)
Vasopressors
1. _Norepinephrine_
- Dose: 0.01-1 mcg/kg/min IV infusion
- Administration: IV infusion
- Use: Hypotension, septic shock
- Indication: Systolic BP < 90 mmHg
- Side effects: Hypertension, tachycardia, peripheral ischemia
- Antidote: None
2. _Epinephrine_
- Dose: 0.01-1 mcg/kg/min IV infusion
- Administration: IV infusion
- Use: Hypotension, cardiac arrest
- Indication: Systolic BP < 90 mmHg, cardiac arrest
- Side effects: Hypertension, tachycardia, arrhythmias
- Antidote: None
3. _Vasopressin_
- Dose: 0.01-0.04 U/min IV infusion
- Administration: IV infusion
- Use: Hypotension, septic shock
- Indication: Systolic BP < 90 mmHg
- Side effects: Hypertension, hyponatremia, peripheral ischemia
- Antidote: None
Inotropes
1. _Dobutamine_
- Dose: 2-20 mcg/kg/min IV infusion
- Administration: IV infusion
- Use: Cardiac failure, cardiogenic shock
- Indication: Low cardiac output, hypotension
- Side effects: Tachycardia, hypertension, arrhythmias
- Antidote: None
2. _Milrinone_
- Dose: 0.125-0.5 mcg/kg/min IV infusion
- Administration: IV infusion
- Use: Cardiac failure, cardiogenic shock
- Indication: Low cardiac output, hypotension
- Side effects: Hypotension, tachycardia, arrhythmias
- Antidote: None
Antiarrhythmics
1. _Lidocaine_
- Dose: 1-4 mg/kg IV bolus, followed by 1-4 mg/kg/h IV infusion
- Administration: IV injection or infusion
- Use: Ventricular arrhythmias
- Indication: VT, VF
- Side effects: CNS toxicity, cardiac depression
- Antidote: None
2. _Amiodarone_
- Dose: 5-10 mg/kg IV bolus, followed by 1-2 mg/kg/h IV infusion
- Administration: IV injection or infusion
- Use: Ventricular arrhythmias, atrial fibrillation
- Indication: VT, VF, AF
- Side effects: Hypotension, bradycardia, thyroid dysfunction
- Antidote: None
Antihypertensives
1. _Nitroglycerin_
- Dose: 0.5-10 mcg/kg/min IV infusion
- Administration: IV infusion
- Use: Hypertension, angina
- Indication: Systolic BP > 180 mmHg
- Side effects: Hypotension, headache, methemoglobinemia
- Antidote: None
2. _Labetalol_
- Dose: 0.1-1 mg/kg IV bolus, followed by 0.01-0.1 mg/kg/h IV infusion
- Administration: IV injection or infusion
- Use: Hypertension
- Indication: Systolic BP > 180 mmHg
- Side effects: Hypotension, bradycardia, bronchospasm
- Antidote: None
3. _Nicardipine_
- Dose: 0.5-5 mcg/kg/min IV infusion
- Administration: IV infusion
- Use: Hypertension
- Indication: Systolic BP > 180 mmHg
- Side effects: Hypotension, tachycardia, peripheral edema
- Antidote: None
4. _Clevidipine_
- Dose: 0.5-16 mcg/kg/min IV infusion
- Administration: IV infusion
- Use: Hypertension
- Indication: Systolic BP > 180 mmHg
- Side effects: Hypotension, tachycardia, headache
- Antidote: None
Anticoagulants
1. _Heparin_
- Dose: 50-100 U/kg IV bolus, followed by 10-20 U/kg/h IV infusion
- Administration: IV injection or infusion
- Use: Thrombosis, embolism
- Indication: DVT, PE, AF
- Side effects: Bleeding, thrombocytopenia
- Antidote: Protamine (1-2 mg IV)
2. _Warfarin_
- Dose: 0.1-0.3 mg/kg PO daily
- Administration: Oral
- Use: Thrombosis, embolism
- Indication: DVT, PE, AF
- Side effects: Bleeding, skin necrosis
- Antidote: Vitamin K (1-2 mg IV)
3. _Fondaparinux_
- Dose: 2.5-5 mg SC daily
- Administration: Subcutaneous injection
- Use: Thrombosis, embolism
- Indication: DVT, PE
- Side effects: Bleeding, thrombocytopenia
- Antidote: None
Antiplatelet Agents
1. _Aspirin_
- Dose: 50-100 mg PO daily
- Administration: Oral
- Use: Thrombosis, embolism
- Indication: MI, stroke, TIA
- Side effects: Bleeding, GI upset
- Antidote: None
2. _Clopidogrel_
- Dose: 75 mg PO daily
- Administration: Oral
- Use: Thrombosis, embolism
- Indication: MI, stroke, TIA
- Side effects: Bleeding, thrombotic thrombocytopenic purpura
- Antidote: None
Vasodilators
1. _Nitroprusside_
- Dose: 0.5-10 mcg/kg/min IV infusion
- Administration: IV infusion
- Use: Hypertension, heart failure
- Indication: Systolic BP > 180 mmHg
- Side effects: Hypotension, cyanide toxicity
- Antidote: None
2. _Hydralazine_
- Dose: 0.1-0.5 mg/kg IV bolus, followed by 0.01-0.05 mg/kg/h IV infusion
- Administration: IV injection or infusion
- Use: Hypertension
- Indication: Systolic BP > 180 mmHg
- Side effects: Hypotension, tachycardia, headache
- Antidote: None
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Other Medications
1. _Mannitol_
- Dose: 0.25-1 g/kg IV bolus
- Administration: IV injection
- Use: Increased intracran
